DOI: 10.1002/ame2.12017
The battle against SARS and MERS coronaviruses:Reservoirs and Animal Models
Shu-ran Gong
Lin-lin Bao
摘要：In humans, infection with the coronavirus, especially the severe acute respiratory syndrome coronavirus (SARS-CoV) and the emerging Middle East respiratory syn-drome coronavirus (MERS-CoV), induces acute respiratory failure, resulting in high mortality. Irregular coronavirus related epidemics indicate that the evolutionary ori-gins of these two pathogens need to be identified urgently and there are still ques-tions related to suitable laboratory animal models. Thus, in this review we aim to highlight key discoveries concerning the animal origin of the virus and summarize and compare current animal models.
机标关键词：
资助基金：This review was supported by the National Key Research and Development Project of China(2016YFD0500304)CAMS Innovation Fund for Medical Sciences(CIFMS)CAMS Innovation Fund for Medical Sciences( 2016-I2M-1-014\2016-12M-006)the Chinese National Major S & T Project(2017ZX10304402-001-003)
论文发表日期：2018-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 125-133 )
英文信息