DOI: 10.1002/ame2.12083
Animal modeling in bone research—Should we follow the White Rabbit?
Aline Schafrum Macedo
Caroline Cezaretti Feitosa
Fernando Yoiti Kitamura Kawamoto
Paulo Vinicius Tertuliano Marinho
ísis dos Santos Dal-Bó
Bianca Fiuza Monteiro
Leonardo Prado
Thales Bregadioli
Gabriel Antonio Covino Diamante
Cassio Ricardo Auada Ferrigno
摘要：Animal models are live subjects applied to translational research. They provide in-sights into human diseases and enhance biomedical knowledge. Livestock devel-opment has favored the pace of human social development over millennia. Today's society is more aware of animal welfare than past generations. The general public has marked objections to animal research and many species are falling into disuse. The search for an ideal methodology to replace animal use is on, but animal mod-eling still holds great importance to human health. Bone research, in particular, has unmet requirements that in vitro technologies cannot fully address. Standardizing novel models remains necessary and rabbits are gaining in popularity as potential bone models. Our aim here is to provide a broad overview of animal modeling and its ethical implications, followed by a narrower focus on bone research and the role rabbits are playing in the current scenario.
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 162-168 )
英文信息