DOI: 10.1002/ame2.12189
Adaptation of mammals to hypoxia
Fang Li1
Zhenglei Qiao1
Qijiao Duan2
Eviatar Nevo3
1.College of Life Sciences and Technology,Mudanjiang Normal University,Mudanjiang,China2.College of Natural Resources and Environment,South China Agriculture University,Guangzhou,China3.Institute of Evolution,University of Haifa,Haifa,Israel
摘要：Oxygen plays a pivotal role in the metabolism and activities of mammals. However, oxygen is restricted in some environments— subterranean burrow systems or habitats at high altitude or deep in the ocean— and this could exert hypoxic stresses such as ox-idative damage on organisms living in these environments. In order to cope with these stresses, organisms have evolved specific strategies to adapt to hypoxia, including changes in physiology, gene expression regulation, and genetic mutations. Here, we review how mammals have adapted to the three high- altitude plateaus of the world, the limited oxygen dissolved in deep water habitats, and underground tunnels, with the aim of better understanding the adaptation of mammals to hypoxia.
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论文发表日期：2021-12-25
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 311-318 )
英文信息