DOI: 10.1002/ame2.12223
Advances in pig models of human diseases
Naipeng Hou1
Xuguang Du2
Sen Wu3
1.College of Animal Science and Technology,China Agricultural University,Beijing,China;Sanya Institute of China Agricultural University,Sanya,China2.Sanya Institute of China Agricultural University,Sanya,China;State Key Laboratory of Agrobiotechnology,College of Biological Sciences,China Agricultural University,Beijing,China3.College of Animal Science and Technology,China Agricultural University,Beijing,China;Sanya Institute of China Agricultural University,Sanya,China;State Key Laboratory of Agrobiotechnology,College of Biological Sciences,China Agricultural University,Beijing,China
摘要：Animal models of human diseases play a critical role in medical research. Pigs are ana-tomically and physiologically more like humans than are small rodents such as mice, making pigs an attractive option for modeling human diseases. Advances in recent years in genetic engineering have facilitated the rapid rise of pig models for use in studies of human disease. In the present review, we summarize the current status of pig models for human cardiovascular, metabolic, neurodegenerative, and various genetic diseases. We also discuss areas that need to be improved. Animal models of human diseases play a critical role in medical research. Advances in recent years in genetic engineering have facilitated the rapid rise of pig models for use in studies of human disease. In the present review, we summarize the current status of pig models for human cardiovascular, metabolic, neurodegenerative, various genetic diseases and xenotransplantation.
机标关键词：humanmodelsadvancesdiseases
论文发表日期：2022-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：12( 141-152 )
英文信息