DOI: 10.1002/ame2.12269
A rare case of giant panda cancer: Pancreatic ductal adenocarcinoma
Yunsheng Wang1
Maohua Xia2
Xiangxiang Li1
Xinxin Guo1
Yan Lu3
Sufen Zhao3
Tianchun Pu2
1.Wildlife Pathological diagnosis Laboratory, Department of Veterinary Hospital , Beijing Zoo , Beijing , China;Beijing Key Laboratory of Captive Wildlife Technologies , Beijing Zoo , Beijing , China2.Beijing Key Laboratory of Captive Wildlife Technologies , Beijing Zoo , Beijing , China;Wildlife Clinical Laboratory, Department of Veterinary Hospital , Beijing Zoo ,Beijing , China3.Beijing Key Laboratory of Captive Wildlife Technologies , Beijing Zoo , Beijing , China
摘要：Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant cancer of the diges-tive system common among humans. However, it is rarely reported in wild animals. In 2018, a giant panda died in the Beijing Zoo. During subsequent histological observa-tion of the pancreas, it was discovered that the glandular epithelial cells had lost the pancreatic acinar structure, tubular areas with obvious structure in the pancreas, and the ductal epithelium was substituted by high columnar mucus cells. Masson stain-ing showed that there were several fibrous tissue proliferative reactions around the ductal adenocarcinoma and immunohistochemical staining revealed that CK7 and CK19 were positively expressed in the pancreatic tissue. Therefore, the pathological diagnosis indicated that the panda had PDAC. In this paper, the panda ' s living condi-tions and pathological diagnosis results are examined, with the aim of providing a reference point for the future diagnosis of wild animal tumors.
机标关键词：pandacancercaserareadenocarcinomaductalgiantpancreatic
论文发表日期：2022-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 582-586 )
英文信息