DOI: 10.1002/ame2.12360
Recent advances in anxiety disorders: Focus on animal models and pathological mechanisms
Hongqing Zhao
Mi Zhou
Yang Liu
Jiaqi Jiang
Yuhong Wang
Science & technology innovation center,Hunan University of Chinese Medicine,Changsha,China
摘要：Anxiety disorders have become one of the most severe psychiatric disorders, and the incidence is increasing every year. They impose an extraordinary personal and socioeconomic burden. Anxiety disorders are influenced by multiple complex and interacting genetic, psychological, social, and environmental factors, which contribute to disruption or imbalance in homeostasis and eventually cause pathologic anxiety. The selection of a suitable animal model is important for the exploration of disease etiology and pathophysiology, and the development of new drugs. Therefore, a more comprehensive understanding of the advantages and limitations of existing animal models of anxiety disorders is helpful to further study the underlying pathological mechanisms of the disease. This review summarizes animal models and the pathogenesis of anxiety disorders, and discusses the current research status to provide insights for further study of anxiety disorders.
机标关键词：anxietyfocusmodelsadvancesanimaldisordersmechanismspathological
论文发表日期：2023-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：14( 559-572 )
英文信息