DOI: 10.1002/ame2.12381
A novel small-animal locomotor activity recording device for biological clock research
Yi-Long Wu1
Ming Zhong2
Jun Yin3
Wei-Jie Ou4
Yu-Bin Zhuang5
Nan-Wen Zhang6
Su Lin7
Yue-Yong Zhu7
1.Endoscopy Center,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China2.Department of Endocrinology,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China3.Chuangke Workshop Technology Co.,Ltd,Shenzhen,China4.Department of Digestive Nutrition,Fujian Children's Hospital,Fuzhou,China5.Experimental Animal Center,Fujian Medical University,Fuzhou,China6.Department of Pharmacology,Fujian Medical University,Fuzhou,China7.Department of Hepatology,Hepatology Research Institute,Clinical Research Center for Liver and Intestinal Diseases of Fujian Province,The First Affiliated Hospital,Fujian Medical University,Fuzhou,China
摘要：The rodent running-wheel recording apparatus is a reliable approach for studying cir-cadian rhythm.This study demonstrated how to construct a simple and intelligent running-wheel recording system.The running wheel was attached to the cage's base,whereas the Hall sensor was attached to the cage's cover.Then,the RJ25 adaptor relayed the running signal to the main control board.Finally,the main control board was connected to the USB port of the computer with the USB connection.Data were collected using the online-accessible,self-created software Magturning.Through Magturning,generated data were saved and exported in real time.Afterward,the device was validated by collecting data on the locomotor activities of mice under dif-ferent light conditions.In conclusion,this new device can record circadian activity of rodents.Our device is appropriate for interdisciplinary investigations related to biological clock research.
机标关键词：activityresearchdeviceclocknovelbiologicallocomotorrecording
论文发表日期：2024-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 71-76 )
英文信息