DOI: 10.1002/ame2.12439
Animal models of tendon calcification:Past,present,and future
Ruichen Li1
Canhao Lai1
Hong Luo1
Yujian Lan1
Xinfang Duan1
Dingsu Bao2
Zhipeng Hou1
Huan Liu1
Shijie Fu1
1.Department of Bone and Joint,The Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou,China2.Department of Bone and Joint,The Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou,China;Chengdu University of Traditional Chinese Medicine,Chengdu,China
摘要：Tendon calcification is a common clinical condition that frequently occurs as a complication after tendon injury and surgery,or as an expression of fibrodysplasia ossificans progressiva.This condition can be referred to by various names in clinical practice and literature,including tendon ossification,tendon mineralization,heterotopic ossification,and calcific tendonitis.The exact pathogenesis of tendon calcification remains uncertain,but current mainstream research suggests that calcification is mostly cell mediated.To further elucidate the pathogenesis of tendon calcification and to better simulate the overall process,selecting appropriate experimental animal models is important.Numerous animal models have been utilized in various clinical studies,each with its own set of advantages and limitations.In this review,we have discussed the advancements made in research on animal models of tendon calcification,with a focus on the selection of experimental animals,the sites of injury in these models,and the methods employed for modeling.
机标关键词：presentfuturemodelspastanimalcalcificationtendon
论文发表日期：2024-08-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：13( 471-483 )
英文信息