DOI: 10.1002/ame2.12516
Rat models of frozen shoulder:Classification and evaluation
Hezirui Gu1
Wenqing Xie2
Hengzhen Li2
Shuguang Liu3
Yusheng Li2
1.Department of Orthopedics,Xiangya Hospital,Central South University,Changsha,China;Xiangya School of Medicine,Central South University,Changsha,China2.Department of Orthopedics,Xiangya Hospital,Central South University,Changsha,China;National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha,China3.Department of Joint Surgery,Honghui Hospital,Xi'an Jiaotong University,Xi'an,China
摘要：Frozen shoulder(FS),also known as adhesive capsulitis,is a condition that causes contraction and stiffness of the shoulder joint capsule.The main symptoms are per-sistent shoulder pain and a limited range of motion in all directions.These symp-toms and poor prognosis affect people's physical health and quality of life.Currently,the specific mechanisms of FS remain unclear,and there is variability in treatment methods and their efficacy.Additionally,the early symptoms of FS are difficult to distinguish from those of other shoulder diseases,complicating early diagnosis and treatment.Therefore,it is necessary to develop and utilize animal models to under-stand the pathogenesis of FS and to explore treatment strategies,providing insights into the prevention and treatment of human FS.This paper reviews the rat models available for FS research,including external immobilization models,surgical internal immobilization models,injection modeling models,and endocrine modeling models.It introduces the basic procedures for these models and compares and analyzes the advantages,disadvantages,and applicability of each modeling method.Finally,our paper summarizes the common methods for evaluating FS rat models.
机标关键词：evaluationmodelsclassificationfrozenshoulder
论文发表日期：2025-01-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 92-101 )
英文信息