DOI: 10.1002/ame2.70045
Strategies for optimization of hypoglycemia rat models
Lee Yeong Zher1
Eason Kong Qi Zheng1
Rayneshia Elaura Raymond2
Ye Zhen Jie3
Christina Gertrude Yap1
1.Jeffrey Cheah School of Medicine and Health Sciences,Monash University,Subang Jaya,Malaysia2.Faculty of Medicine,University of Malaya,Kuala Lumpur,Malaysia3.Faculty of Medicine,Bioscience and Nursing,MAHSA University,Kuala Lumpur,Malaysia
摘要：This review focuses on rat models for studying the short-term and long-term effects of mild and severe hypoglycemia.We explored the physiological mechanisms to un-derstand the consequences of hypoglycemia in rat experimental models.This study aims to investigate the therapeutic potential of phytotherapeutic agents and their efficacy in mitigating the adverse effects of hypoglycemia.Insights from our planned research will be beneficial in improving quality of life for individuals at risk of epi-sodes of low blood sugar.Optimizing hypoglycemic rat models for research requires selecting a suitable experimental model that will be susceptible to hypoglycemia in-duction,effective monitoring of blood glucose levels,and maintaining a high survival rate throughout the required experimental duration.
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论文发表日期：2025-09-30
在线出版日期：2025-10-28（本平台首次上网日期，不代表文献的发表时间）
页数：21( 1590-1610 )
英文信息