Research progress of HPV-associated oropharyngeal cancer
Yue Zhang1
Yiqian Wang1
Qing Li2
Meihua Wang3
1.Department of Pathology,Changzhou Cancer Hospital Affiliated to Soochow University,Changzhou 213032,Jiangsu,China2.Department of Pathology,Changzhou First People's Hospital Affiliated to Soochow University,Changzhou 213004,Jiangsu,China3.Department of Pathology,Changzhou Cancer Hospital,Changzhou,China
摘要：The incidence of oropharyngeal squamous cell carcinomas(OPSCC)is rising rapidly in recent years,while the pathologic mechanisms mediating tumorigenesis are heterogeneous and complex.Indeed,the proportion of OPSCCs mediated by human papillomavirus(HPV)is also increasing,which is named as HPV+OPSCC.In addition,HPV+OPSCCs have distinct biological characteristics,while their intratumoral cell heterogeneity and extratumoral immune microenvironment have guiding significance for clinical treatment decision making and prognosis prediction.In this review,we briefly summarize the overview of HPV and OPSCCs,and discuss the research progress of HPV+OPSCCs in detail.
机标关键词：researchcancerhpv-associatedoropharyngealprogress
论文发表日期：2024-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 41-49 )
英文信息