Pharmaceutical care for septicemia following incomplete spon-taneous abortion:a case report
Guorong Shi1
Jia Luo2
Yan Chen3
Xiang Fu1
1.Department of Pharmacy,Shidong Hospital of Shanghai Yangpu District,Shanghai 200082,China2.Department of Pharmacy,Shanghai Children's Medical Center,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China3.Department of Pharmacy,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China
摘要：We report a case of a 25-year-old pregnant woman at 15 weeks and 4 days of gestation who presented with mas-sive vaginal bleeding and syncope.She was diagnosed with incomplete spontaneous abortion,hemorrhagic shock,acute renal failure,and ketoacidosis.Emergency interventions included fluid resuscitation,blood transfusion,uter-ine evacuation,and continuous venovenous hemofiltration(CVVH).Due to septicemia,empirical anti-infective therapy with meropenem and vancomycin was initiated,guided by therapeutic drug monitoring(TDM)to optimize dosing.Over the course of treatment,the patient's renal function improved,the infection was controlled,and she was stabilized and transferred to a general ward.This case highlights the challenges of managing sepsis and renal failure in pregnancy,emphasizing the critical role of TDM in optimizing antibiotic therapy.It underscores the im-portance of individualized treatment strategies in improving outcomes for high-risk pregnant patients and provides valuable insights for the management of similar cases.
机标关键词：reportcasecareabortionfollowingincompletepharmaceuticalsepticemia
论文发表日期：2025-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 74-79 )
英文信息