Percutaneous vertebroplasty versus percutaneous kyphoplasty for the treatment of delayed post-traumatic vertebral body collapse (Kümmell’s disease) in Chinese patients: a systematic review and meta-analysis
Peng-Fei Han
Cheng-Long Chen
Tao-Yu Chen
Zhi-Liang Zhang
Xiao-Dong Li
Peng-Cui Li
Xiao-Chun Wei
1.Department of Orthopaedic Surgery, The Second People’s Hospital of Changzhi, Changzhi, Shanxi 046000, China2.Department of Orthopaedic Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030009, China
摘要：Objective: To compare the clinical efficacy between percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of Kümmell’s disease in Chinese patients. Methods: The studies using randomized controlled trials to compare clinical efficacy between PVP and PKP in the treatment of Kümmell’s disease in Chinese patients were retrieved from Embase, Pubmed, Central, Cinahl, PQDT, CNKI, CQVIP, Wanfang Data, and CBM (from September 2008 to September 2018). Keywords for both Chinese and English search were: percutaneous vertebroplasty, PVP, percutaneous kyphoplasty, PKP, and Kümmell’s disease. A total of 132 articles were retrieved based on the search strategy through online database searching and manual searching. Finally, one foreign report and seven Chinese reports were included. After extracting the data, statistical software Review Manager 5.3 was used for data analysis. Results: Through comparison, Cobb angle (95% CI [0.54, 4.42), P = 0.01] and Oswestry Dysfunction Index (ODI) (95% CI [0.21, 2.15], P= 0.02) of PKP group was smaller than that of PVP group. Postoperative anterior vertebral body height of the PKP group was better than PVP group (95% CI [?1.27, ?0.66], P < 0.001]. However, the PVP group had shorter operation time than PKP group (95% CI [?13.48, ?7.43), P = 0.001]. In the other outcome measures, including Visual Analogue Scale (VAS) score (95% CI [?0.04, 0.27), P = 0.15), cement volume (95% CI [?0.82, 0.32], P = 0.39) and cement leakage (95% CI [0.90, 2.76], P = 0.11), there was no significant differences between the two procedures. Conclusions: At this stage, there is sufficient evidence to support that PKP is better than PVP in the treatment of Kümmell’s disease in Chinese patients. Although PVP surgery requires much less operation time, PKP has better postoperative radiological results and lower ODI. Moreover, both of them had similar clinical results (e.g., analgesic effects, cement dosage, and leakage rate). Further evidence is dependent on the emergence of randomized controlled trials with higher quality and larger sample sizes in the future.
机标关键词：Chinese patientsrandomized controlled trialspercutaneous vertebroplastyclinical efficacyoperation timeVisual Analogue Scalesearch strategydata analysis
资助基金：National Project of International Science and technology Cooperation program of China(2015DFA33050)National Natural Science Foundation of China for Youths(81601949)
论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 273-283 )
英文信息