Effects of relaxation breathing exercise on fatigue and cortisol level among Indonesian gynecological cancer patients undergoing chemotherapy:a pilot study
Mulhaeriah Mulhaeriah1
Mohammad Syafar Sangkala2
Syahrul Syahrul2
Rezki Wahyuni3
1.Department of Maternity Nursing,Faculty of Nursing,Hasanuddin University,Makassar South Sulawesi 90245,Indonesia2.Department of Medical Surgical Nursing,Faculty of Nursing,Hasanuddin University,Makassar,South Sulawesi 90245,Indonesia3.Hasanuddin University Hospital,Makassar,South Sulawesi 90245,Indonesia
摘要：Objective:This study aimed to determine the effect of the relaxation breathing exercise(RBE)on fatigue and cortisol levels among Indonesian women with gynecological cancer undergoing chemotherapy.
Methods:This pilot study consecutively recruited 44 gynecological cancer patients to receive RBE(22)or usual care(22).Cortisol level was measured before and after completion of the intervention(day 8).Fatigue was measured using the Piper Fatigue Scale(PFS).Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale(HADS)at the baseline days of the study for days 1,4,and 8.The obtained data were analyzed using Fisher's exact test,the independent t-test,and the Mann-Whitney U test.
Results:There were significant increases in cortisol levels within the groups,either the intervention or control groups,respectively(P-value=0.0003 and 0.001).Despite there being no statistical significance between the intervention and control groups,there were noticeable differences in the cortisol levels,indicating the extreme increase in cortisol levels in the control group(Median[IQR1-IQR3]:2.30[0.99-9.09];Min-Max:0.43-23.38)compared with the intervention group(Median[IQR1-IQR3]=2.97[1.26-5.18];Min-Max=0.39-6.91).
Conclusions:RBE helps prevent a significant increase in cortisol levels that can alleviate fatigue for women with gynecological cancer.Further research was recommended to compare several intervention modalities for fatigue and cancer-related symptom management based on cortisol level changes.
机标关键词：cortisolfatiguecancerpilotstudylevelamongbreathing
论文发表日期：2024-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 201-208 )
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