Effect of Carvedilol on the Coronary Vascular Endothelial Function after Percutaneous Transluminal Coronary Angioplasty
苏显明
马奕
崔长琮
1.Geriatric and Cardiovascular Department, First Hospital of Xi an Jiaotong University, Xian 710061 China2.Geriatric and Cardiovascular Department, First Hospital of Xi an Jiaotong University, Xian 710061 China3.Geriatric and Cardiovascular Department, First Hospital of Xi an Jiaotong University, Xian 710061 China
摘要：Objectives To understand the effect of carvedilol on the coronary vascular endothelial function of the patients with coronary heart disease after percutaneous transluminal coronary angioplasty (PTCA). Methods 51cases, having one or more than two branches narrow ( ≥ 70% ) , were diagnosed by coronary angiography. These patients were divided randomly into carvedilol group (n = 28 ) and control group (n = 23) who did not take carvedilol.Endothelin (ET) and nitro dioxide (NO) levels of peripheral blood were measured before and after PTCA,before and after two weeks by taking carvedilol. Results Compared with the ET and NO levels before PTCA, ET were markedly increased and NO were decreased after PTCA (p ＜ 0.05); compared with the ET and NO levels before taking carvedilol, ET were decreased and NO were increased after two week (p ＜0.05) , but the ET and NO levels of the control group did not change in the period of two weeks observation (p ＞ 0.05). Conclusions Carvedilol may improve the coronary vascular endothelial function after PTCA.
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论文发表日期：2003-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 90-92 )
英文信息