Association of serum lipoprotein (α) and prognosis of acute coronary syndrome patients with desirable low-density lipoprotein level
YI Shi-xin
TAN Hong
ZHANG Ying
DONG Hao-jian
ZHOU Ying-ling
摘要：Background It has been reported that elevated serum lipoprotein α(α)[ Lp (α)] increased cardiovascular risk. However, whether this effect is independent of serum low-density lipoprotein (LDL) remains controversial. Methods One hundred and seventy-nine acute coronary syndrome patients with desirable low-density lipoprotein level( <2.59 mmol/L), were divided into lipoprotein (α) elevated group (70 cases) and lipoprotein (α) normal group (109 patients). Successful percutaneous coronary intervention (PCI) were performed before discharge. After 6-month follow-up, the adverse events of death, myocardial infarction, heart failure, progression of coronary lesions and in-stent stenosis were evaluated. Results There was higher rate of adverse events in the lipoprotein (α) elevated group than in the normal group (2s.7%vs 8.3%, P = 0.001). By logistic regression analysis, odds ratio of elevated serum lipoprotein (α) was 3.846 (95%CI 1.615,9.157, P = 0.002).Conclusion Elevated serum lipoprotein (α) was associated with poor prognosis of acute coronary syndrome patients with desirable low-density lipoprotein level.
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分类号：R541.4(心脏、血管（循环系）疾病)
论文发表日期：2011-04-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
英文信息