Contrast-induced nephropathy after staged percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease
MA Gui-zhou
XU Rong-he
WANG Ying
CHEN Shao-min
NI Chu-min
CAI Zhi-xiong
摘要：Background Contrast-induced nephropathy (CIN) occurs frequently in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) and is associated with poor outcomes.Multivessel coronary artery disease (MVCAD) is considered to be a potentially important risk factor for CIN.There are still no data on CIN in patients undergoing staged PCI for STEMI and MVCAD.Therefore,we explored the incidence,risk factors,in-hospital and follow-up outcomes of CIN in this special population.Methods From 2011 to 2018,we enrolled 103 consecutive patients with STEMI who underwent staged PCI for MVCAD.CIN was defined as a relative increase of ＞ 25％ or an absolute increase of ≥ 0.5 mg/dL in SCr from the baseline value 72 h after exposure to the contrast medium.The incidence,risk factors,in-hospital and follow-up outcomes of CIN in this special population were studied.Results We found 1) the incidence of CIN after primary PCI and staged PCI was 16.50％ and 25.20％,respectively.2) patients with CIN had worse in-hospital and follow-up outcomes.3) in multivariate logistic analysis,independent risk factors for CIN included:① lower creatinine clearance at baseline;② atrioventricular block requiring temporary cardiac pacemaker implantation;③ use of IABP at baseline;④ total contrast volume administered (primary PCI + staged PCI);⑤ shorter time interval between primary PCI and staged PCI.Conclusions CIN is a frequent complication in patients with STEMI and MVCAD undergoing staged PCI.The development of CIN is associated with worse in-hospital and follow-up outcomes.
机标关键词：
论文发表日期：2018-09-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：14( 143-156 )
英文信息