The relationship between CDK13 and TBAD patients undergoing TEVAR
LIU Hui-Ling
GUAN Jin-zhen
FENG Yu-liang
HUANG Wei
CAI Liu-yang
JIANG Lei
LUO Jian-fang
FANG Hui-min
摘要：Type B aortic dissections (TBAD) are catastrophic conditions with high complication and mortality rates.This study aimed to investigate the prognostic significance of CDK13 expression in patients with type B aortic dissection (TBAD) undergoing thoracic endovascular aortic repair (TEVAR).Methods Totally 56 patients with TBAD undertaken TEVAR were included in this study,CDK13 expression was detected in blood samples which were collected from vein before angiography.We reviewed hospital readmission records and outpatient clinic interviews for possible events.The primary endpoint was long-term all-cause mortality.The secondary endpoints were in-hospital major adverse clinical events (MACEs).Results A total of 56 patients (mean age 61.2±12.4 years) were included in the study.We divided the patients into 2 risk levels (28 patients for each level) according to the median of CDK13 expression.The in-hospital mortality (3.6％ vs.14.2％,P＜0.05) and MACEs (10.7％ vs.39.3％,P＜0.05) were significant higher in patients with high CDK13 level (≥median).Conclusions The expression level of CDK13 could be considered as a relatively simple tool for pre-TEVAR risk stratification.
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 121-124,130 )
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