Research on the therapeutic prospect of exosomal miR-122-5p and miR-206 in treatment of chronic heart failure
FAN Lin-lin1
ZHONG Yuan-yuan1
Nomi Adnan2
ZHANG Jin-guo3
1.Jining Medical University, Jining 272067, Shandong, China2.Jining Medical University, School of International Education, jining 272067, Shandong, China3.The Second Department of Cardiology, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China
摘要：Backrround Exosomes are bilayer lipid membranous vesicles with a diameter of 40-100nm.They play an important role in signal transduction among cellular substances.Exosomes miR-206 and miR-122-5 have been found to play a regulatory role in cardiovascular diseases such as chronic heart failure,and therefore have gradually become the focus of various studies.The review has introduced the biological characteristics of the exosomal microRNAs,the association between exosomes miR-122-5p,miR-206 and chronic heart failure,and briefly described the therapeutic prospects of these two exosomal miRNAs in the treatment of chronic heart failure.It may provide some new directions for the diagnosis and treatment of heart failure.
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论文发表日期：2020-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 147-153 )
英文信息