Advances in research of epicardial adipose tissue and diastolic heart failure
QIN Yi-ran1
Nomi Adnan2
ZHONG Yuan-yuan3
ZHANG Jin-guo4
1.Cheeloo College of Medicine, Shandong University,Jinan 250012, Shandong, China2.Jining Medical University,School of International Education, Jining 272067, Shandong,China3.Jining Medical University, Jining 272067, Shan-dong, China4.The Second Department of Cardiology, Affili-ated Hospital of Jining Medical University, Jining 272029,Shandong, China
摘要：Background Epicardial adipose tissue(EAT)is a unique visceral adipose tissue that is located between the myocardium and the visceral layer of the pericardium.Physiologically,EAT can produce heat and protect the heart.Under pathological conditions,EAT is involved in the development of diastolic heart failure(DHF)by se-creting a variety of pro-inflammatory cytokines.More and more studies have shown that EAT plays an important role in the inflammatory mechanism and myocardial remodeling of DHF.Exercise,weight loss and drug therapy can significantly reduce the thickness/volume of EAT and its functional disorder.In recent years,research on EAT and DHF has made new progress.This article reviewed the mechanism and treatment of EAT in the develop-ment of DHF.
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论文发表日期：2020-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 285-291 )
英文信息