Initial clinical outcomes of new directional coronary atherectomy devices—Coronary atherectomy guided by intravascular ultrasound
CHEN Yi-yue1
NISHIO Soji2
FUJITA Shinya2
TSUJI Takafumi2
KYO Eisho2
1.Fuwai Hospital Chinese Academy of Medical Scienc-es,China;Shenzhen Sun Yat-sen Cardiovascular Hospital,China2.Kusatsu Heart Center,Japan
摘要：Objective:Stenting for coronary artery disease is generally accepted as a percutaneous coronary intervention(PCI),but there remain many challenges with this approach.Directional coronary atherectomy(DCA)can reduce plaque volume,and its use alone or in combination with drug-coated balloons can reduce stent implanta-tion.However,clinical studies on DCA are limited,and its safety and effectiveness remain unclear.We aimed to evaluate the safety and effectiveness of the new DCA device-ATHEROCUT with intravascular ultrasound(IVUS)guidance.Methods:Between May 2015 and May 2018,45 patients with 48 lesions were treated electively with ATHEROCUT in Kusatsu Heart Center.We retrospectively analyzed in-hospital major adverse cardiac events(MACE),overall clinical follow-up MACE,complications rate,and dual antiplatelet therapy(DAPT)duration.Our definition of MACE included cardiac death,myocardial infarction,and target lesion revascularization(TLR).Our definition of complications included coronary perforation,thrombosis,and major bleeding.Results:The overall follow-up rate was 95.6％,and the average follow-up period was 453±320 days.In-hospital and overall MACE rates were 2.2％(TLR 0)and 11.1％(TLR 8.9％),respectively.There were no complications,except for one cere-bral hemorrhage case(2.1％),which was considered irrelevant to the PCI procedure.The DAPT duration was 8.3±8.3 months,only 4.8±4.9 months in the subgroup that did not require another PCI.Conclusion:Using the ATH-EROCUT device with IVUS guidance is safe,might be effective in selected patients and can shorten the DAPT peri-od.
机标关键词：ultrasoundclinicaldevicesatherectomycoronarydirectionalguidedinitial
论文发表日期：2022-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 153-161 )
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