Association between menopause and hypertension in women:A population-based cross-sectional study
NONG Yu-xin1
LU Jun-quan2
WU Di1
Qiu Hong-rui3
WEI Xue-biao4
YU Dan-qing1
1.Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou,510080 China;Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention,Guangdong Provincial People's Hospital,(Guangdong Academy of Medical Sciences),Southern Medical University,510080 China2.Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention,Guangdong Provincial People's Hospital,(Guangdong Academy of Medical Sciences),Southern Medical University,510080 China;Shantou University Medical College,Shantou,515063,China3.Guangzhou University of Chinese Medicine,Guangzhou,510080 China;Department of Thoracic Surgery,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical Univer-sity,510080 China4.Department of Geriatric Intensive Medicine,Guangdong Provincial Geriatrics Institute,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,510080 China
摘要：Background Objectives:Menopause is a critical stage in women's life,and both menopausal and postmeno-pausal women are at risk of developing hypertension.However,the association between menopause and hyperten-sion lacks sufficient study.This study aimed to investigate the relationship between menopause and hypertension in women.Methods:The participant inclusion criteria were age ≥18 and being female,while the exclusion criteria were having no record of menopause and being unable to determine the presence of hypertension.Data from 1,884 Chinese women from the China Health and Retirement Longitudinal Study were included for analysis,and the asso-ciation between menopause and hypertension in women was determined by conducting multivariate logistic regres-sion and excluding potential confounding factors by subgroup analysis.Results:The prevalence of hypertension in menopausal women was overall higher than in non-menopausal women(39.3％vs 23.6％),and the difference was statistically significant(P＜0.000).Overall,statistically significant differences emerged for age,total cholesterol,low-density lipoprotein cholesterol,estimated glomerular filtration rate,hemoglobin levels,income status,and place of residence between postmenopausal and premenopausal women(P＜0.05).Menopause is associated with hy-pertension(OR:1.65 95％CI:1.22-2.21 P＜0.001).However,this relationship was limited to those aged 50-60 years(OR:1.965 95％CI:1.295-2.98),and no association was observed at other ages.Conclusions:Women are at further increased risk of developing hypertension after menopause.In particular,the risk of hypertension in women with middle and early menopause should be of concern.
机标关键词：hypertensionassociationpopulationbetweenstudybasedcross-sectionalmenopause
论文发表日期：2023-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 8-16 )
英文信息