Early curative effect of extracorporeal membrane oxygenation in the treatment of fulminant myocarditis and its influence on prognosis
HUANG Zhe1
LI Jing1
WANG Hui1
YU Zi-ying2
TAN Wei-hua2
YAO Lan1
1.Intensive Care Unit,Yueyang Central Hospital,Yue Yang 414000,Hu Nan Province,China2.Department of Emer-gency,The First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang 421000,Hu Nan Prov-ince,China
摘要：Background Adult Fulminant myocarditis(FM)is the more serious form of acute myocarditis,and extracorpo-real membrane oxygenation(ECMO)is an effective adjunction that helps to maintain circulation while providing adequate treatment.The blood supply of vital organs is guaranteed,which helps patients to survive the acute attack and improves the survival rate of FM.Methods In this study,50 clinical data of adult FM patients received in our hospital from July 2018 to July 2023 were collected for retrospective analysis.According to different treatment methods,they were divided into ECMO group(n=25)and non-ECMO group(n=25).After 14 days of treatment,the level of left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),creatine kinase isoenzymes(CK-MB),cardiac troponin I(cTnI)and brain natri-uretic peptide(BNP),and the incidence of complications were compared between the two groups.Results Before treatment,there was no significant difference in cardiac function between the two groups(P＞0.05).After 14 days of treatment,ECMO group showed greater decline than non-ECMO group in LVESD and LVEDD,and LVEF was higher than that in the non-ECMO group(P＜0.05).The level of CK-MB,cTnl and BNP in ECMO group were lower than those in non-ECMO(P＜0.05).The overall incidence of complications was 8％in the ECMO group,which was lower than 32％in the non-ECMO group(P＜0.05).Conclusions The early efficacy of ECMO treatment in adult patients with FM is considerable,which is conducive to improving the cardiac function of patients and preventing complications.
机标关键词：prognosiscurativeearlyeffectextracorporealfulminantinfluencemembrane
论文发表日期：2024-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 117-122 )
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