The predictive role of postoperative carbon dioxide combining power for in-hospital mortality in elderly patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
XIAO Ji-chen
DU Su-ling
LIAO You-wan
Department of Geriatric Intensive Medicine,Guangdong Provincial Geriatrics Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou 510080,China
摘要：Background The prognosis of elderly patients with ST-segment elevation myocardial infarction(STEMI)is poor,and information on specific risk factors remains scarce.We aimed to investigate the prevalence and the prog-nostic impact of postoperative carbon dioxide combining power(CO2CP)in elderly STEMI patients receiving PCI.Methods Patients ≥65 years old with the diagnosis of STEMI who had received PCI was retrospectively enrolled between January 2010 and April 2016 in the Guangdong Provincial People's Hospital.The association between postoperative CO2CP and in-hospital and 1-year mortality was evaluated.Results A total of 775 elderly patients with STEMI were included and divided into two groups according to the lower normal limits of CO2CP:＜22 mmol/L(n=180),and ≥22 mmol/L(n=595).The incidence of in-hospital death(12.2％vs.4.2％,P＜0.001),acute kidney injury(25.0％vs.13.3％,P＜0.001)and major adverse clinical events(30.0％vs.8.7％,P＜0.001)were signif-icantly higher in patients with a low CO2CP.Multivariate logistic regression analysis showed an independent relationship between CO2CP and in-hospital death[odd ratio(OR):0.88,95％confidential interval(CI):0.80-0.97,P=0.010].This relationship disappeared in one-year mortality[hazard ratio(HR):0.95,95％CI:0.89-1.01,P=0.116].Conclusions Postoperative CO2CP is a feasible predictor during hospitalization for elderly patients with STEMI receiving PCI.[S Chin J Cardiol 2024;25(4):238-244]
机标关键词：percutaneousst-segmentdioxidecarbonpowerrolewithcombining
论文发表日期：2024-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 238-244 )
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