Clinical correlation between myeloperoxidase and acute coronary syndrome
Jie Wang
Yanwei Xing
Changsheng Ma
Shihong Li
Zhizhong Li
Yonghong Gao
Yibing Nong
摘要：Objective To study whether myeloperoxidase (MPO) can provide prognostic information in patients with acute coronary syndromes (ACS). Methods The study population consisted of 274 consecutive patients with ACS. All patients underwent coronary angiography which showed significant coronary artery disease and blood samples were collected at admission. Follow-ups were scheduled at 1, 3, and 6 months.The end point included cardiac death, acute myocardial infarction (MI), percutaneous or surgical revascularization. Results Patients with elevated MPO serum levels (MPO ≥ 72.2 AUU/L) were more likely to have diabetics and had a history of coronary events. Kaplan-Meier event rate curves with accumulative incidence of end point at 6-month follow-up in the MPO ≥ 72.2 AUU/L group was significantly higher than in MPO＜72.2 AUU/L group. Conclusions MPO may be a powerful predictor of adverse outcome in patients with ACS.
机标关键词：
分类号：R5(内科学)
资助基金：国家重点基础研究发展计划（973计划）(2003CB517103)
论文发表日期：2007-10-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 209-212 )
英文信息