Long-term outcomes of PCI vs.CABG for ostial/midshaft lesions in unprotected left main coronary artery
Cheng-Long GUO
Xian-Peng YU
Bang-Guo YANG
Meng-Meng LI
Ji-Qiang HE
Quan LI
Cheng-Xiong GU
Shu-Zheng LYU
Jian-Zeng DONG
摘要：Background There are limited data on long-term (＞ 5 years) outcomes of drug-eluting stent (DES) implantation compared with coronary artery bypass grafting (CABG) for ostial/midshaft left main coronary artery (LMCA) lesions.Methods Of the 259 consecutive patients in Beijing Anzhen Hospital with ostial/midshaft LMCA lesions,149 were treated with percutaneous coronary intervention (PCI) with DES and 110 were with CABG.The endpoints of the study were death,repeat revascularization,myocardial infarction (MI),stroke,the composite of cardiac death,and major adverse cardiac and cerebrovascular events (MACCE,the composite of cardiac death,MI,stroke or repeat revascularization).The duration of follow-up is 7.1 years (interquartile range 5.3 to 8.2 years).Results There is no significant difference between the PCI and CABG group during the median follow-up of 7.1 years (interquartile range:5.3-8.2 years) in the occurrence of death (HR:0.727,95％ CI:0.335-1.578;P =0.421),the composite endpoint of cardiac death,MI or stroke (HR:0.730,95％ CI:0.375-1.421;P =0.354),MACCE (HR:1.066,95％ CI:0.648-1.753;P =0.801),MI (HR:1.112,95％ CI:0.414-2.987;P =0.833),stroke (HR:1.875,95％ CI:0.528--6.659;P =0.331),and repeat revascularization (HR:1.590,95％ CI:0.800-3.161;P =0.186).These results remained after multivariable adjusting.Conclusion During a follow-up up to 8.2 years,we found that DES implantation had similar endpoint outcomes compared with CABG.
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论文发表日期：2017-10-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 254-260 )
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