Minimally invasive thalamic hematoma drainage can improve the six-month outcome of thalamic hemorrhage
Wen-Ming LIU
Xue-Guang ZHANG
Ze-Li ZHANG
Gang LI
Qi-Bing HUANG
摘要：Objective To explore predictors of the 6-month clinical outcome ofthalamic hemorrhage,and evaluate if minimally invasive thalamic hematoma drainage (THD) could improve its prognosis.Methods A total of 54 patients with spontaneous thalamic hemorrhage were evaluated retrospectively.Clinical data,including demographics,stroke risk factors,neuroimaging variables,Glasgow Coma Score (GCS) on admission,surgical strategy,and outcome,were collected.Clinical outcome was assessed using a modified Rankin Scale,six months after onset.Univariate analysis and multivariate logistic regression analysis were performed to determine predictors of a poor outcome.Results Conservative treatment was performed for five patients (9.3％),external ventricular drainage (EVD) for 20 patients (37.0％),THD for four patients (7.4％),and EVD combined with THD for 25 patients (46.3％).At six months after onset,21 (38.9％) patients achieved a favorable outcome,while 33 (61.1％) had a poor outcome.In the univariate analysis,predictors of poor 6-month outcome were lower GCS on admission (P =0.001),larger hematoma volume (P ＜ 0.001),midline shift (P =0.035),acute hydrocephalus (P =0.039),and no THD (P =0.037).The independent predictors of poor outcome,according to the multivariate logistic regression analysis,were no THD and larger hematoma volume.Conclusions Minimally invasive THD,which removes most of the hematoma within a few days,with limited damage to perihematomal brain tissue,improved the 6-month outcome of thalamic hemorrhage.Thus,THD can be widely applied to treat patients with thalamic hemorrhage.
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论文发表日期：2017-10-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 266-273 )
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