Non-invasive ventilation improves hemorheology status in hypoxemic patients with acute myocardial infarction after PCI
Xi-Fu WANG
Ming YE
Dong YAN
Hui-Min ZHANG
Ping JIA
Xue-Jun REN
Yu-Jie ZENG
摘要：Background Hypoxemia sometimes occurs in the emergency room in the patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI),even in those with administration of conventional high-flow oxygen inhalation.The objective of the present study was to evaluate the effectiveness of non-invasive ventilation (NIV) in improving blood oxygen content and hemorheology in patients with AMI and hypoxemia.Methods This prospective study enrolled 50 consecutive eligible patients with AMI (aged 72.3 ± 9.5 years),who had undergone PCI and been administered high-flow oxygen but still had hypoxemia.Blood was taken before NIV and at 0.5,1,and 2 h after NIV.Blood gases,hemorheological variables including erythrocyte deformability,erythrocyte aggregation,erythrocyte osmotic fragility,membrane fluidity,and oxidative stress level were measured.Results Blood PaO2 increased to normal by 1 h after NIV.Assessed hemorheological variables had all improved and plasma malondialdehyde concentration decreased significantly after 2 h of NIV.Conclusions Our data suggest that NIV can help to improve blood oxygen content,hemorheological status,and minimize plasma lipid peroxidation injury in hypoxemic patients with AMI who have undergone PCI.
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论文发表日期：2017-10-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 274-279 )
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