Should atrial fibrillation patients with hypertension as an additional risk factor of the CHA2DS2-VASc score receive oral anticoagulation?
Juan WANG
Da-Peng ZHANG
Hong-Bin LIU
Jiu-Chang ZHONG
Xin-Chun YANG
摘要：Hypertension has been found to be increased a risk of stroke in atrial fibrillation (AF).Both the European and U.S.guidelines advocate the use of the CHA2DS2-VASc (congestive heart failure,hypertension,age ＞ 75 years,diabetes mellitus,stroke/transient ischemic attack,vascular disease,age 65-74 years,sex category) scheme for risk stratification.Although vitamin K antagonists is more effective than acetylsalicylic acid at preventing ischaemic stroke,its benefit is offs by an increased haemorrhage risk.The risk of ischemic stroke in patients with AF and a CHA2DS2-VASc score of 1 are considered to be low risk and may be not expected to benefit from anticoagulation therapy.Hypertension carries an increased risk of ischemic stroke,however,it is also a clear risk factor for hemorrhage in AF.Therefore,the optimal antithrombotic management is highlighted in patients with AF with only one risk factor especially hypertension.
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论文发表日期：2018-03-08
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 229-234 )
英文信息