Long-term follow-up of quality of life in high-risk patients undergoing transcatheter aortic valve implantation for symptomatic aortic valve stenosis
Marjo JAG De Ronde-Tillmans
Tom AJ de Jager
Jeannette A Goudzwaard
Nahid El Faquir
Nicolas M van Mieghem
Felix Zijlstra
Elisabeth MWJ.Utens
Francesco US Mattace-Raso
Mattie J Lenzen
Peter PT de Jaegere
摘要：Background Transcatheter aortic valve implantation (TAVI) has become the standard treatment for patients with severe symptomatic aortic stenosis (AS) considered at very high risk for surgical aortic valve replacement.The purpose of this sub-study was to evaluate long-term (＞ 4 years) health-related quality of life (QoL) in octogenarians who underwent TAVI.Methods A single center observational registry in twenty patients who underwent flame analysis assessment ≥ 4 years after TAVI.Health-related QoL was evaluated,using the Short Form-36 (SF-36),the EuroQoL-5D (EQ-5D) and the visual analogue score (EQ-VAS) questionnaires.Results The mean SF-36 subscale scores at follow-up were physical functioning 40.8 ± 26.3,role physical functioning 67.7 ± 34.9,vitality 54.6 ± 21.6,general health 52.1 ± 20.4,social functioning 63.8 ± 37.7,role emotional functioning 70.2 ± 36.0,mental health 73.2 ± 23.3 and bodily pain 80.9 ± 22.9.The mean EQ-VAS score ＞ 4 years after TAVI was 64.7 ± 15.1.With respect to functional class,80％ of the patients were in NYHA class Ⅰ/Ⅱ at follow-up compared to 15％ prior to TAVI.Conclusions This sub-study reports a significant improvement in functional class (NYHA) in a selected group of very elderly patients ＞ 4 years after TAVI.Furthermore,all patients showed a satisfactory QoL despite their age and multiple comorbidities.In addition,our study reveals a lower QoL when compared with the general age matched Dutch population.
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论文发表日期：2018-04-10
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 261-267 )
英文信息