Anemia in patients with Takayasu arteritis: prevalence, clinical features, and treatment
Ying ZHANG
Di ZHANG
Yi QU
Peng FAN
Ya-Xin LIU
Hui-Min ZHANG
Lei SONG
Wen-Jun MA
Hai-Ying WU
Jun CAI
Fang LUO
Xian-Liang ZHOU
De-Yu ZHENG
Li-Sheng LIU
摘要：Background Anemia is a common comorbidity of patients with Takayasu arteritis (TA).This study evaluated the prevalence,clinical characteristics,and treatment in Chinese TA patients with anemia.Methods This retrospective study included 533 consecutive patients hospitalized for TA from January 2009 to April 2018.Anemia was diagnosed on the basis of hemoglobin level,according to World Health Organization criteria.Results A total of 194 patients (36.4％) were diagnosed with anemia.Most had mild anemia (177,91.2％).Female patients were predominant (92.8％ of anemic patients).Normocytic anemia (62.9％) was the most common pattem.Anemic patients were more likely than non-anemic patients to have dizziness (29.4％ vs.21.2％),low body mass index (22.0 ± 3.6 vs.22.9 ± 3.4 kg/m2),and active disease stage (64.9％ vs.50.1％);pulmonary involvement (12.4％ vs.26.8％),pulmonary hypertension (12.9％ vs.20.1％) and pulmonary hypertensive-target drugs (2.8％ vs.11.6％) were less common among anemic than non-anemic patients (all P ＜ 0.05).Larger left ventricular end-diastolic diameter and lower left ventricular ejection fraction were observed in anemic patients.Over a median follow-up of four months,the increase of hemoglobin in anemic patients was associated with the use of iron supplementation.Conclusions Anemia is a very common concurrent condition in TA,especially in young,female patients.Patients with anemia are more likely to be in the active disease stage.Iron supplementation helps increase hemoglobin.
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 689-694 )
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