Beneficial effects of moderate to vigorous physical activity on cardiovascular disease among Chinese adults
Qiong LIU1
Fang-Chao LIU1
Ke-Yong HUANG1
Jian-Xin LI1
Xue-Li YANG1
Xin-Yan WANG1
Ji-Chun CHEN1
Xiao-Qing LIU2
Jie CAO1
Chong SHEN3
Ling YU4
Fang-Hong LU5
Xian-Ping WU6
Lian-Cheng ZHAO1
Ying LI1
Dong-Sheng HU7
Xiang-Feng LU1
Jian-Feng HUANG1
Dong-Feng GU1
1.Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing, China;Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China2.Division of Epidemiology, Guangdong Provincial People's Hospital and Cardiovascular Institute, Guangzhou, China3.Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China4.Department of Cardiology, Fujian Provincial Hospital, Fuzhou, China5.Cardio-Cerebrovascular Control and Research Center, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China6.Sichuan Center for Disease Control and Prevention, Chengdu, China7.Department of Prevention Medicine, Shenzhen University School of Medicine, Shenzhen, China
摘要：Background In China,lack of evidence remains a significant challenge for the national initiative to promote physical activity (PA).We aimed to quantify the beneficial effects of meeting or maintaining the recommended PA level [150 minutes per week (min/wk) of moderate PA or 75 min/wk of vigorous PA or an equivalent combination] on incident cardiovascular disease (CVD) among Chinese population.Methods We included 100,560 participants without history of CVD from three cohorts in the Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project.Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95％ confidence intervals (CIs) for CVD events and its subtypes,including stroke,coronary heart disease,heart failure,and CVD death.Results During a median follow-up of 7.3 years (range:6-15 years),777,163 person-years and 4693 incident CVD events were observed.Compared with participants who were inactive at baseline,the multivariable adjusted HR (95％ CI) of developing CVD was 0.74 (0.69-0.79) for those who met recommended moderate to vigorous physical activity (MVPA) level at baseline.Furthermore,the risk of CVD incidence was reduced with increment of MVPA (Ptrend ＜ 0.001),and the HR (95％ CI) of highly-active versus inactive category was 0.62 (0.56-0.68).Compared with individuals who were inactive both at the baseline and follow-up,those keeping active over the period of follow-up had a substantial lower risk of incident CVD with the HR (95％ CI) of 0.57 (0.43-0.77).Conclusions The findings demonstrated that meeting and maintaining the recommended MVPA level could reduce the cardiovascular risk.Wider adoption of the PA recommendations would have considerable health impacts to the Chinese population.
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论文发表日期：2020-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 85-95 )
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