Hearing loss and cognitive decline among older adults with atrial fibrillation:the SAGE-AF study
Wei-Jia WANG1
Darleen Lessard2
Hawa Abu2
David D.McManus3
Tanya Mailhot4
Jerry H.Gurwitz5
Robert J.Goldberg2
Jane Saczynski4
1.Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA2.Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA3.Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA;Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA4.Department of Pharmacy and Health System Sciences, Northeastern University, Boston, MA, USA5.Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA;Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA
摘要：Objective To examine the association between hearing loss and cognitive fimction cross-sectionally and prospectively among older adults with atrial fibrillation (AF).Methods Patients with AF ≥ 65-year-old (n =1244) in the SAGE (Systematic Assessment of Geriatric Elements)-AF study were recruited from five internal medicine or cardiology clinics in Massachusetts and Georgia.Hearing was assessed by a structured questionnaire at baseline.Cognitive function was assessed by Montreal Cognitive Assessment (MoCA) at baseline and one year.Cognitive impairment was defined as score ≤ 23 on the MoCA.The associations between hearing loss and cognitive function were examined by multivariable adjusted logistic regression.Results Participants with hearing loss (n =451,36％) were older,more likely to be male,and have depressive symptoms than patients without hearing loss.At baseline,528 (42％) participants were cognitively impaired.Individuals with hearing loss were significantly more likely to have cognitive impairment at baseline[adjusted odds ratio (OR) =1.37,95％ confidence interval (CI): 1.05-1.81].Among the 662 participants who did not have cognitive impairment at baseline and attended the one-year follow-up visit,106 (16％) developed incident cognitive impairment.Individuals with,versus those without,hearing loss were significantly more likely to develop incident cognitive impairment at one year (adjusted OR =1.68,95％ CI: 1.07-2.64).Conclusions Hearing loss is a prevalent but under-recognized factor associated with cognitive impairment in patients with AF.Assessment for hearing loss may be indicated among these patients to identify individuals at high-risk for adverse outcomes.
机标关键词：
论文发表日期：2020-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 177-183 )
英文信息