Twelve-year outcomes after revascularization for ostial/shaft lesions in unprotected left main coronary artery
Xian-Peng YU
Yu LI
Ji-Qiang HE
Ze-Ning JIN
摘要：Objective To evaluate a very long-term clinical outcomes of patients treated with coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for ostial/shaft lesions in unprotected left main coronary artery (ULMCA).Methods & Results A total of 472 patients with isolated ostial/shaft lesions in ULMCA were enrolled,who received DES implantation or underwent CABG between January 2003 and July 2009 in Beijing Anzhen Hospital.The major endpoints of this study were death,repeat revascularization,non-procedural myocardial infarction (MI) and stroke.The median follow-up was twelve years (interquartile range:9.4-14.0 years) in the overall patients.There were no significant differences of incidence of death (23.3％ vs.25.6％,P =0.227),repeat revascularization (27.3％ vs.28.4％,P =0.423),non-procedural MI (20.0％ vs.14.5％,P =0.561),and stroke (6.1％ vs.9.3％,P =0.255)between PCI and CABG groups before multivariate adjusting.After adjusting covariates with multivariate Cox hazard regression model,there were still no significant differences between PCI and CABG groups.Conclusions During the median follow-up of twelve years,we found that PCI with DES was as effective and safe as CABG in patients with left main ostial/shaft lesion in this observational study.
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论文发表日期：2020-06-28
页数：6( 338-343 )
英文信息