Comparison of outcomes for percutaneous coronary intervention in men and women with unprotected left main disease
Sheng-Wen LIU1
Chang-Dong GUAN2
Feng-Huan HU1
Jue CHEN1
Ke-Fei DOU1
Wei-Xian YANG1
Yong-Jian WU1
Yue-Jin YANG1
Bo XU2
Shu-Bin QIAO1
1.Department of Cardiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences,Beijing,China2.Catheterization Laboratories,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences,Beijing,China
摘要：BACKGROUND Percutaneous coronary intervention(PCI)in patients with unprotected left main coronary artery disease(UL-MCAD)is increasing strategy in coronary artery patients.However,there is a lack of knowledge on the impact of sex on out-comes of patients undergoing ULMCAD PCI.METHODS From January 2004 to December 2015,there were 3,960 patients undergoing ULMCAD PCI at our institution,in-cluding 3,121(78.8％)men and 839(21.2％)women.The clinical outcome included the incidence of major adverse cardiac events(MACE)(the composite of all-cause death,myocardial infarction(MI),and revascularization),all-cause death,MI,revasculariza-tion at three years follow-up.RESULTS Compared with men,women had not significantly different MACE(14.7％vs.14.6％,P = 0.89,all-cause death(3.5％vs.3.7％,P= 0.76),MI(5.0％vs.4.3％,P= 0.38),revascularization(9.1％vs.8.9％,P= 0.86),respectively.After adjustment,rates of MACE(HR = 1.49;95％CI:1.24-1.81;P＜0.0001)and all-cause death(HR = 1.65;95％Cl:1.09-2.48;P= 0.017)occurred more fre-quently in male patients,as well as revascularization(HR = 1.46;95％CI:1.16-1.85;P= 0.001).CONCLUSION In this analysis,compared to men,women undergoing ULMCAD PCI have better outcomes of MACE,all-cause death,and revascularization.
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论文发表日期：2021-03-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 168-174 )