Are women more susceptible to ischemic heart disease compared to men? A literature overview
Masoud Majidi1
Vahid Eslami2
Pardis Ghorbani1
Mahnoosh Foroughi2
1.Clinical Research and Development Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran2.Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
摘要：Ischemic heart disease (IHD) is known as the leading cause of death in both genders.Moreover,significant sex differences were found in cardiac structure,function,pathophysiology,presentation,treatment,and outcome of IHD.The presence of unique risk factors such as exposure to menarche and pregnancy,more anemia,hypertension,and autoimmune disorders in women have recently received attention.Ischemic symptoms are more indefinite and vague in women compared to men as well as a delay in diagnosis,treatment,and worse outcomes compared to men.Women usually receive less evidence-based treatment and intervention,with less concern on preventive health care.Clinical trials primarily recruit male patients and women are underrepresented.Without any correct diagnosis,treatment,and prevention,these problems are accumulated and continue up to older age.Accordingly,with the belief of longer life in women and the increased prevalence of IHD with aging,it will become an important public health problem and concern in the future.This narrative review aimed to provide an overview of some of the differences between the two genders in terms of IHD with paying more attention to practical points.
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论文发表日期：2021-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 289-296 )