Frailty in patients undergoing transcatheter aortic valve replacement:from risk scores to frailty-based management
Andreas Tzoumas1
Damianos G.Kokkinidis2
Stefanos Giannopoulos3
George Giannakoulas4
Leonidas Palaiodimos5
Dimitrios V Avgerinos6
Polydoros N Kampaktsis7
Robert T.Faillace2
1.Aristotle University of Thessaloniki,Thessaloniki,Greece2.Department of Medicine,Jacobi Medical Center,Albert Einstein College of Medicine,Bronx,USA3.Division of Cardiology,Rocky Mountain Regional VA Medical Center,University of Colorado,Denver,USA4.First Cardiology Department,AHEPA University Hospital,Aristotle University of Thessaloniki,Thessaloniki,Greece5.Department of Medicine,Jacobi Medical Center,Albert Einstein College of Medicine,Bronx,USA;Division of Hospital Medicine,Montefiore Medical Center,Albert Einstein College of Medicine,Bronx,USA6.Department of Cardiothoracic Surgery,New York-Presbyterian/Weill Cornell Medical Center,New York,USA7.Division of Cardiology,New York University Langone Medical Center,New York,USA
摘要：Aortic stenosis (AS) is the most common valvular disease in the western coun-tries and is associated with aging.[12]Transcatheter aortic valve replacement (TAVR) now offers a therapeutic option for elderly patients who are deemed inoperable and is an excellent alternative for those who are considered high-risk for surgical valve replacement.[3,4] However,mortality after TAVR is still high with one-year and two-year mortality rates of 24.3％ and 33.9％,respectively.[5] Thus,util-ization of effective risk stratification tools before TAVR cannot be overstated.[5-8] Currently,EUROSCORE Ⅱand the Society of Thoracic Surgery score are the re-commended risk models to predict postoperative mortality in cardiac surgery,however,they were not designed to be used for TAVR patients.[6,8] The main limitation in the implementation of these models is that they do not take into account frailty.[9]Frailty assessment could not only offer incremental prognostic information but could also theoretically improve outcomes with preoperative or postoperative management and modification of specific frailty components.[10,11]
机标关键词：
论文发表日期：2021-06-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 479-486 )