Periprocedural complications and one-year outcomes after catheter ablation for treatment of atrial fibrillation in elderly patients: a nationwide Danish cohort study
Jesper Nielsen1
Kristian Hay Kragholm1
Sofie Brix Christensen1
Arne Johannessen2
Christian Torp-Pedersen3
Steen Buus Kristiansen4
Peter Karl Jacobsen5
Peter Steen Hansen6
Mogens Stig Djurhus7
Christoffer Polcwiartek1
Peter S?gaard1
Anna Margrethe Th?gersen1
Uffe Jakob Ortved Gang8
Ole Dan J?rgensen9
Filip Lyng Lindgren1
Sam Riahi10
1.Department of Cardiology,Aalborg University Hospital,Denmark2.Department of Cardiology,Gentofte Hospital,Copenhagen University Hospital,Denmark3.Department of Cardiology,Aalborg University Hospital,Denmark;Department of Clinical Research and Cardiology,Nordsjaellands Hospital,Hiller?d,Denmark4.Department of Cardiology,Skejby University Hospital,Denmark5.Department of Cardiology,Rigshospitalet,Copenhagen University Hospital,Denmark6.Department of Cardiology,Rigshospitalet,Copenhagen University Hospital,Denmark;M?lholm Clinic,Vejle,Denmark7.Department of Cardiology,Odense University hospital,Denmark8.Department of Cardiology,Roskilde University Hospital,Denmark9.Department of Thoracic Surgery,Odense University Hospital,Denmark10.Department of Cardiology,Aalborg University Hospital,Denmark;AF-Study group Aalborg University Hospital,Denmark;Clinical Institute,Aalborg University,Denmark
摘要：OBJECTIVES To investigate complications within 30-days following first-time ablation for atrial fibrillation (AF), including a composite of cardiac tamponade, hematoma requiring intervention, stroke or death, in patients ≥ 75 years of age, compared to pa-tients aged 65?74 years. In addition, one-year all-cause mortality and AF relapse were compared. METHODS & RESULTS All patients receiving their first catheter ablation for AF between 2012 and 2016 were identified us-ing Danish nationwide registries. Patients aged 65?74 years served as the reference group for patients ≥ 75 years. Relapse of AF within one year was defined as cardioversion following a three-month blanking period, re-ablation or confirmed relapse within follow-up. The composite complication outcome did not differ between the two age groups, with 39/1554 (2.8％) in patients 65?74 years of age, versus 5/199 (2.5％) in older patients (adjusted HR = 0.94), 95％ CI: 0.37?2.39, P = 0.896). Patients ≥ 75 years or older had no increased hazard of death within 30 days after the procedure, with an incidence of 3/1554 (0.2％) in younger pa-tients and 2/199 (1.0％) in patients ≥ 75 years of age (adjusted HR = 4.71, 95％ CI: 0.78?28.40, P = 0.091). There was no difference in relapse of AF after one year between age groups (≥ 75 years adjusted HR = 1.00, 95％ CI: 0.78-1.26, P = 0.969). CONCLUSION In patients ≥ 75 years of age selected for catheter ablation for AF, the incidence of periprocedural complica-tions, as well as one-year freedom from AF showed no statistical difference, when compared to patients 65?74 years of age.
机标关键词：studyafterablationatrialcathetercohortcomplicationsdanish
论文发表日期：2021-11-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 897-907 )