Association between heart failure severity and mobility in geriatric patients: an in-clinic study with wearable sensors
Tobias Braun1
Anna Wiegard2
Johanna Geritz2
Clint Hansen2
Kim Eng Tan2
Hanna Hildesheim2
Jennifer Kudelka2
Corina Maetzler2
Julius Welzel2
Robbin Romijnders2
Walter Maetzler2
Philipp Bergmann3
1.Department of Neurology,Kiel University,Arnold-Heller-Stra?e 3,24105 Kiel,Germany;Department of Applied Health Sciences,Division of Physiotherapy,Hochschule für Gesundheit(University of Applied Sciences),Gesundheits-campus 6-8,44801 Bochum,Germany;HSD Hochschule D?pfer(University of Applied Sciences),Waidmarkt 3 und 9,50676 Cologne,Germany2.Department of Neurology,Kiel University,Arnold-Heller-Stra?e 3,24105 Kiel,Germany3.Department of Internal Medicine I,Christian-Albrechts-University of Kiel,Arnold-Heller-Stra?e 3,24105 Kiel,Germany
摘要：BACKGROUND Individuals with heart failure (HF) frequently experience limitations in mobility, but specific aspects of these limitations are not well understood. This study investigated the association of HF severity, based on the New York Heart Associ-ation (NYHA) classes, with digital mobility outcomes (DMOs) and handgrip strength in older inpatients with HF. METHODS For this explorative analysis, hospital admission and discharge data from an ongoing, prospective cohort study were used. The sample included older participants with HF and a sub-sample of heart-healthy individuals. Participants were equipped with a wearable inertial measurement unit (IMU) system during mobility performance (balancing, sit-to-stand transfer, walking). We analyzed the association between 17 DMOs and HF severity with multiple linear regression models. RESULTS The total sample included 61 older participants (65–97 years of age, 55.7％ female). Of all DMOs, only sway path in a semi-tandem stance position (m/s2) showed a relevant association with NYHA classes (admission: β = ?0.28, P = 0.09; discharge:β = ?0.39, P = 0.02). Handgrip strength showed a trend towards a significant association (admission: β = ?0.15, P = 0.10; discharge:β = ?0.15, P = 0.19). CONCLUSIONS This is to our best knowledge the first analysis on the association of HF severity and IMU-based DMOs. Sway path and handgrip strength may be the most promising parameters for monitoring mobility aspects in treatment of HF.
机标关键词：associationmobilitybetweenheartstudywithfailuregeriatric
论文发表日期：2022-09-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：15( 660-674 )