His bundle pacing versus left bundle branch pacing on ven-tricular function in atrial fibrillation patients referred for pacing:a prospective crossover comparison
Yang YE1
Bo GAO2
Yuan LV3
Tian-Tian XU1
Si-Si ZHANG4
Xiao-Li LU5
Ying YANG1
Dong-Mei JIANG1
Yi-Wen PAN1
Xia SHENG1
Bei WANG6
Yan-Kai MAO6
Zu-Wen ZHANG1
Shi-Quan CHEN1
Jie-Fang ZHANG1
Li WANG1
Jiang-Fen JIANG1
Ya-Xun SUN1
Yan MA1
Fei-Ling WANG1
Min WANG1
Hong HE1
Chen-Yang JIANG1
Guo-Sheng FU1
1.Department of Cardiology,Sir Run Run Shaw Hospital,College of Medicine,Zhejiang University,Hangzhou,Zhejiang Province,China2.Department of Cardiology,Sir Run Run Shaw Hospital,College of Medicine,Zhejiang University,Hangzhou,Zhejiang Province,China;Department of Cardiology,Zhejiang Rongjun Hospital,Jiaxing,Zhejiang Province,China3.Department of Cardiology,Sir Run Run Shaw Hospital,College of Medicine,Zhejiang University,Hangzhou,Zhejiang Province,China;Depart-ment of Cardiology,Lishui People's Hospital,Lishui,Zhejiang Province,China4.Department of Cardiology,Ningbo Ninth Hospital,Ningbo,Zhejiang Province,China5.Department of Cardiology,Anji people's Hospital,Ningbo,Zheji-ang Province,China6.Department of Diagnostic Ultrasound and Echocardiography,Sir Run Run Shaw Hospital,Col-lege of Medicine,Zhejiang University,Hangzhou,Zhejiang Province,China
摘要：BACKGROUND His bundle pacing (HBP) and left bundle branch pacing (LBBP) both provide physiologic pacing which main-tain left ventricular synchrony. They both improve heart failure (HF) symptoms in atrial fibrillation (AF) patients. We aimed to assess the intra-patient comparison of ventricular function and remodeling as well as leads parameters corresponding to two pa-cing modalities in AF patients referred for pacing in intermediate term. METHODS Uncontrolled tachycardia AF patients with both leads implantation successfully were randomized to either modal-ity. Echocardiographic measurements, New York Heart Association (NYHA) classification, quality-of-life assessments and leads parameters were obtained at baseline and at each 6-month follow up. Left ventricular function including the left ventricular endo-systolic volume (LVESV), left ventricular ejection fraction (LVEF) and right ventricular (RV) function quantified by tricuspid an-nular plane systolic excursion (TAPSE) were all assessed. RESULTS Consecutively twenty-eight patients implanted with both HBP and LBBP leads successfully were enrolled (69.1 ± 8.1 years, 53.6％ male, LVEF 59.2％ ± 13.7％). The LVESV was improved by both pacing modalities in all patients (n = 23) and the LVEF was improved in patients with baseline LVEF at less than 50％ (n = 6). The TAPSE was improved by HBP but not LBBP (n =23). CONCLUSION In this crossover comparison between HBP and LBBP, LBBP was found to have an equivalent effect on LV function and remodeling but better and more stable parameters in AF patients with uncontrolled ventricular rates referred for at-rioventricular node (AVN) ablation. HBP could be preferred in patients with reduced TAPSE at baseline rather than LBBP.
机标关键词：bundlefunctionbranchatrialcomparisoncrossoverfibrillationleft
论文发表日期：2023-01-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 51-60 )