Feasibility and clinical benefits of the double-ProGlide technique for hemostasis after cryoballoon atrial fibrillation ablation with uninterrupted oral anticoagulants
Jia-Yin SUN1
Chang-Bo XUAN2
Hai-Liang YU3
Hai-Yang WANG4
Hong-Ya HAN1
Zhi-Ming ZHOU1
De-An JIA1
Dong-Mei SHI1
Yu-Jie ZHOU1
Shi-Wei YANG1
1.Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing Institute of Heart Lung and Bl-ood Vessel Disease,the Key Laboratory of Remodeling-Related Cardiovascular Disease,Ministry of Education,Beijing,Ch-ina2.Department of Cardiology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing,China3.Depar-tment of Cardiology,Tangshan Fengrun District Second People's Hospital,Hebei,China4.Department of Cardiology,Qi-ngdao Municipal Hospital,Qingdao,China
摘要：OBJECTIVE To access the efficacy and safety of the double-ProGlide technique for the femoral vein access-site closure in cryo-balloon ablation with uninterrupted oral anticoagulants (OAC), and its impact on the electrophysiology laboratory time as well as hospital stay after the procedure in this observational study. METHODS Patients with atrial fibrillation undergoing cryoballoon ablation with uninterrupted OAC at Department of Cardi-ology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China from May 2019 to May 2021 were enrolled in this study. From October 2020, double-ProGlide technique was consistently used for hemostasis (ProGlide group), and before that convent-ional manual compression was utilized (manual compression group). The occurrence of vascular and groin complications was acce-ssed during the hospital stay and until the three-month follow-up. RESULTS A total of 140 participants (69.30％ of male, mean age: 59.21 ± 10.29 years) were evaluated, 70 participants being in each group. Immediate hemostasis was achieved in all the patients with ProGlide closure. No major vascular complications were found in the ProGlide group while two major vascular complications were occurred in the manual compression group. The incidence of any groin complication was obviously higher in subjects with manual compression than patients with ProGlide devices (15.71％ vs. 2.86％, P = 0.009). In addition, compared with the manual compression group, the ProGlide group was associated with significa-ntly shorter total time in the electrophysiology laboratory [112.0 (93.3–128.8) min vs. 123.5 (107.3–158.3) min, P = 0.006], time from sheath removal until venous site hemostasis [3.8 (3.4–4.2) min vs. 8.0 (7.6–8.5) min, P < 0.001], bed rest time [8.0 (7.6–8.0) h vs. 14.1 (12.0–17.6) h, P < 0.001] and hospital stay after the procedure [13.8 (12.5–17.8) h vs. 38.0 (21.5–41.0) h, P < 0.001]. CONCLUSIONS Utilization of the double-ProGlide technique for hemostasis after cryoballoon ablation with uninterrupted OAC is feasible and safe, which has the clinical benefit in reducing the total electrophysiology laboratory time and the hospital stay len-gth after the procedure.
机标关键词：hemostasisclinicalafterwithoralablationanticoagulantsatrial
论文发表日期：2023-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 268-275 )