Minimally invasive valve surgery: pushing boundaries over the eighty
Cristina Barbero1
Dario Brenna1
Antonio Salsano2
Marco Pocar3
Erik Cura Stura1
Claudia Calia1
Viviana Sebastiano1
Mauro Rinaldi1
Davide Ricci2
1.Department of Cardiovascular and Thoracic Surgery,Cittàdella Salute e della Scienza,University of Turin,Turin,Italy2.Department of Integrated Surgical and Diagnostic Sciences,University of Genoa,Genoa,Italy3.Department of Cardiovascular and Thoracic Surgery,Cittàdella Salute e della Scienza,University of Turin,Turin,Italy;Department of Clini-cal Sciences and Community Health,University of Milan,Milan,Italy
摘要：BACKGROUND Mean age of patients with valves diseases is significantly increasing, and, in the near future, cardiac surgeons will have to deal with a considerable number of patients aged more than 80 years. The remarkable results gained by the minimally invasive approach have encouraged its application in more complex and fragile patients, such as older people. This study aimed to identify the rate of early mortality and major complications, and independent predictors for mid-term mortality in octogenarians undergoing minimally invasive valve surgery. METHODS Octogenarian patients undergoing right mini-thoracotomy mitral and/or tricuspid valve surgery between 2006 and 2020 were included. Primary endpoint was to identify independent predictors for mid-term mortality, and secondary endpoints we-re operative morality, stroke, independent predictors for early composite outcome, and quality of life at follow-up. RESULTS Analysis was performed on 130 patients. Stroke occurred in one patient (0.8％), while operative mortality was 6％ (eight patients). One-year and five-year survival were 86％ and 64％, respectively. Logistic regression identified age and creatinine level as independent predictors of mid-term mortality, survival analysis showed that age ≥ 84 years and creatinine level ≥ 1.22 mg/dL were the cut-off points for worst prognosis. Female gender and hypertension were found to be independent predictors of early co-mposite outcome. CONCLUSIONS Results of the present study show that age alone should not be considered a contraindication for minimally invasive valve surgery. Identifying patients who are most likely to have survival and functional benefits after surgery is decisive to achieve optimal health outcomes and prevent futile procedures.
机标关键词：surgeryoverboundarieseightyinvasiveminimallypushingvalve
论文发表日期：2023-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 276-283 )