Independent prognostic value of the congestion and renal index in patients with acute heart failure
Run-Qing JI1
Bin WANG1
Jin-Guo ZHANG2
Shu-Hong SU3
Li LI4
Qin YU5
Xian-Yan JIANG6
Xin FU7
Xue-Hua FANG8
Xiao-Wen MA9
Ao-Xi TIAN10
Jing LI1
1.National Clinical Research Center for Cardiovascular Diseases,NHC Key Laboratory of Clinical Research for Cardi-ovascular Medications,State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,National Center for Cardiovascular Diseases,Beijing,China;Fuwai Hos-pital,Chinese Academy of Medical Sciences,Shenzhen,China2.Department of Cardiology,Affiliated Hospital of Jin-ing Medical University,Jining,China3.Department of Cardiology,Xinxiang Central Hospital,Xinxiang,China4.De-partment of Cardiology,Shanxi Fenyang Hospital,Fenyang,China5.Department of Cardiology,Affiliated Zhongshan Hospital of Dalian University,Dalian,China6.Heart Center,Qingdao Fuwai Cardiovascular Hospital,Qingdao,China7.Department of Cardiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou,China8.Department of Cardiology,Beijing Liangxiang Hospital,Beijing,China9.Department of Cardiology,Qinyang People's Hospital,Qinyang,China10.National Clinical Research Center for Cardiovascular Diseases,NHC Key Laboratory of Clinical Research for Cardi-ovascular Medications,State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,National Center for Cardiovascular Diseases,Beijing,China
摘要：BACKGROUND Clinical outcomes are poor if patients with acute heart failure(AHF)are discharged with residual congestion in the presence of renal dysfunction.However,there is no single indication to reflect the combined effects of the two related pathophysiological processes.We,therefore,proposed an indicator,congestion and renal index(CRI),and examined the associ-ations between the CRI and one-year outcomes and the incremental prognostic value of CRI compared with the established scor-ing systems in a multicenter prospective cohort of AHF.METHODS We enrolled AHF patients and calculated the ratio of thoracic fluid content index divided by estimated glomerular filtration rate before discharge,as CRI.Then we examined the associations between CRI and one-year outcomes. RESULTS A total of 944 patients were included in the analysis(mean age 63.3±13.8 years,39.3％women).Compared with pa-tients with CRI≤0.59 mL/min per kΩ,those with CRI＞0.59 mL/min per kΩ had higher risks of cardiovascular death or HF hos-pitalization(HR = 1.56[1.13-2.15])and all-cause death or all-cause hospitalization(HR = 1.33[1.01-1.74]).CRI had an increment-al prognostic value compared with the established scoring system.CONCLUSIONS In patients with AHF,CRI is independently associated with the risk of death or hospitalization within one year,and improves the risk stratification of the established risk models.
机标关键词：congestionheartindexwithacutefailureindependentpatients
论文发表日期：2023-07-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 516-526 )