Association between stress hyperglycemia ratio and in-hospi-tal outcomes:findings from the improving Care for Cardiovas-cular Disease in China-Acute Coronary Syndrome(CCC-ACS)Project
Wen-Jie WANG
Ke-Xin WANG
Jia-Long NIU
Yi-Xuan LIU
Hai-Long GE
Hua SHEN
On behalf of CCC-ACS investigators
Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing,China
摘要：BACKGROUND Stress hyperglycemia ratio(SHR)could provide accurate information on the acute status of hyperglycemia.The relationship between SHR and acute coronary syndrome(ACS)prognosis remains unclear.This study was conducted to id-entity the association between SHR and in-hospital outcomes in patients with ACS.
METHODS A total of 12,010 patients were eventually enrolled in the study.The relationship between SHR and in-hospital ma-jor adverse cardiovascular events(MACEs)was then modeled by restricted cubic spline(RCS)curves,and all patients were divi-ded into three groups according to the results.The multivariate logistic regression analysis was used to determine the associati-ons between the SHR and in-hospital outcomes,described as odds ratios(ORs)and 95％confidence intervals(CIs).Subgroup analy-ses were also performed on different diseases.
RESULTS The median age of this cohort was 63(54,71)years old,and 8942(74.5％)were male.Group 1 was defined as SHR＜0.6(n=426),Group 2 was defined as SHR between 0.6 and 1(n=5821),and Group 3 was defined as SHR＞1(n=5763).Compared wi-th Group 2,Group 1(OR=1.891,95％CI:1.028-3.479,P＜0.001)and Group 3(OR=1.868,95％CI:1.434-2.434,P＜0.001)had higher risks of suffering from in-hospital MACEs.SHR was associated with higher risks of in-hospital MACEs in the subgroups of DM[OR=2.282,95％CI:1.477-3.524).
CONCLUSIONS Both low and high SHR levels were independently associated with in-hospital MACEs.Young males with DM,hypertension,and decreased renal function had much higher risks of suffering from SHR-correlated MACEs.
机标关键词：associationprojectbetweenstresscarefromcardiovas-cularchina-acute
论文发表日期：2024-06-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 658-668 )