Clinical impact of drug-coated balloon treatment of coronary artery disease in elderly patients
Eun-Seok SHIN1
Mi Hee JANG1
Sunwon KIM2
Dong Oh KANG3
Ki-Bum WON4
Bitna KIM1
Ae-Young HER5
1.Department of Cardiology,Ulsan University Hospital,University of Ulsan College of Medicine,Ulsan,South Korea2.Cardiovascular Center,Department of Internal Medicine,Korea University Ansan Hospital,Korea University College of Medicine,Ansan,South Korea3.Cardiovascular Center,Department of Internal Medicine,Korea University Guro Hospital,Korea University College of Medicine,Seoul,South Korea4.Division of Cardiology,Chung-Ang University Gwangmyeong Hospital,Gwangmyeong,Gyeong,South Korea5.Division of Cardiology,Department of Internal Medicine,Kangwon National University College of Medicine,Kangwon National University School of Medicine,Chuncheon,South Korea
摘要：Background Data on drug-coated balloon(DCB)treatment in elderly patients are limited.This study was to evaluate the effic-acy of DCB treatment in percutaneous coronary intervention(PCI)among elderly patients.
Methods A retrospective analysis included 232 patients aged 75 years or older with coronary artery disease who underwent successful PCI using either DCB alone or in combination with drug-eluting stent(DES)based on pre-dilation results(DCB-based PCI).These patients were compared with 1818 elderly patients who underwent second-generation DES implantation(DES-only PCI).The endpoint was major adverse cardiovascular events(MACE)at 2-year follow-up.
Results In the DCB-based PCI,61.2％of patients received DCB-only treatment.Compared to DES-only PCI,the DCB-based PCI group had fewer stents(0.5±0.7 and 1.7±0.8,P＜0.001),shorter stent lengths(13.3±20.9 mm and 37.4±23.0 mm,P＜0.001),and lower usage of small stents with a diameter of 2.5 mm or less(15.6％and 28.7％,P=0.010).The DCB-based PCI group exhibited lower rate of MACE(5.5％and 13.1％,P=0.003),target vessel revascularization(1.1％and 5.6％,P=0.017)and major bleeding(0.7％and 5.1％,P=0.009)at 2-year follow-up.The reduced risk in 2-year MACE was consistently observed across various match-ing procedures,with the most significant reduction noted in target vessel revascularization and major bleeding.
Conclusion The DCB-based PCI reduced stent burden,particularly in the usage of small diameter stents,and was associated with lower risks of MACE,target vessel revascularization,and major bleeding compared to DES-only PCI in elderly patients.
机标关键词：clinicalimpactarteryballooncoronarydiseasedrug-coatedelderly
论文发表日期：2025-01-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 150-158 )