A Study on the Ultrastructure and Gene Location of Hereditary Gingival Fibromatosis
杨明华
张东生
肖尚喜
武影
郑际烈
孔祥银
1.Medical College of Nanjing University2.3.4.Medical College of Nanjing University5.Medical College of Nanjing University
摘要：Objective To ascertain the histological characteristics of hereditary gingival fibromatosis and the location of HGF gene. Methods A pedigree analysis of HGF was made. The ultrastructure of gingival overgrown tissue was observed by electron microscopy (EMS) and the location of the HGF gene defined with microsatellite markers. Results The HGF consisted of coarse collagen bundles and fibrocytes, epithelial cells, smooth muscle cells, etc. were abnormally arranged; the HGF locus had been mapped to chromosome 5q13-q22. Conclusion The gingival pathological changes resemble "hamartoma" and the findings have implications for identification of the underlying genetic basis of HGF.
机标关键词：
分类号：R3(基础医学)
论文发表日期：2002-04-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 80-84 )
英文信息