Study of the immunoisolating effects of barium-alginate microencapsulation on rat islets allograft survival
Mei Zhang
Chao Liu
Cuiping Liu
Youwen Qin
Zhaosun Zhen
摘要：Objective: To evaluate the immunoisolating effects of barium-alginate microencapsulation on islets allograft survival. Methods: The nonmicroencapsulated and microencapsulated islets were transplanted under the kidney capsule or intraperitoneally into Wistar rat with STZ-induced diabetes. The blood glucose and insulin secretion of grafts were observed. Graft function was tested by oral rats was associated with normal glucose and insulin profiles in response to OGTT. Conclusion: Microencapsulation with barium-alginate membrane can prolong islet survival and protect islets against allorejection.
机标关键词：
资助基金：江苏省卫生厅135工程医学重点人才基金(2001-31)
论文发表日期：2005-03-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 81-85 )
英文信息