The Different Expression of PPARγ in the Artery Tissues of Hypertensive Patients with Different Ages
Yongqin Li
Xiaolin Niu
Shijie Wang
Shaomin Li
Jiancang Ma
摘要：Objective: To study the expression of the peroxisome proliferator-activated receptor γ(PPARγ) in the artery tissues of essential hypertensive patients, and the different changes with different ages, especially to the hypertensive patients more than 65 years old.Methods: Collected the mesenteric artery tissues of essential hypertensive patients( ＞65 years old group and ＜65 years old group)and patients with normal blood pressure,using immunohistochemical analysis and image acquiring and analysis system to detect the expression of PPARγ in the artery tissues. Results: the expression of PPARγ in the artery tissues of essential hypertensive patients is higher than that in the patients with normal blood pressure( P ＜ 0.05), and to the group of hypertensive patients, the expression of PPARγ in ＞ 65 years old group is higher than that in ＜ 65 years old group ( P ＜ 0.05). Conclusion: the expression of PPARγ in artery tissues is increased in hypertensive patients than in the patients with normal blood pressure, and increased with aging in hypertensive patients, suggesting that PPARγhas great relationship with hypertension.
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分类号：R5(内科学)
论文发表日期：2005-07-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 191-193 )
英文信息