Study on the migration of nerve stem cell in vitro Induced by glioma cells
Yilu Gao
Shuzi Gao
Yi Fen
Sheyu Lin
Mei Liu
摘要：Objective: Previous studies have shown that glioma cells induced thc migration of nerve stem cells (NSCs)in vivo. This study was exploring whether this situation could happen in vitro. Methods: Supematant from C6 glioma cell lines or astrocytes cultured in serum-free medium growing in logarithmic phase were separately placed in lower chambers and NSCs were placed in the upper chambers of Trans-well culture system. After 36 h co-incubation, these NSCs spheres occurred on the middle membrane were counted. Results: Results demonstrated that the supernatant from C6 glioma cell culture, not from the astrocytes, enhanced the migration of NSCs ( P ＜0.01). Conclusion: Some components in C6 glioma cell culture can atract the migration of NSCs.
机标关键词：
分类号：R73(肿瘤学)
资助基金：江苏省自然科学基金(BK2002145)
论文发表日期：2005-11-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 325-328 )
英文信息