Study on Vip protein expression in psoriatic epidermis with the topical treatment of capsaicin ointment
Chunshui Yu
Yanping Xi
Shengshun Tan
摘要：Objective: To investigate the mechanism of capsaicin in treating active psoriasis vulgaris. Methods: VIP protein in active psoriatic lesions before and 30 days after the treatment of capsaicin ointment was detected by immunohistochemistry. Results:There was positive expression of VIP in all layers of psoriatic lesions epidermis (95.5 % ), but after the treatment of capsaicin ointment,there was nearly no expression of VIP protein in epidermis(22.2% ). Conclusion: Capsaicin inhibits proliferation and induces the differentiation of keratinocytes through down-regulating the expression of VIP in psoriatic epidermis.
机标关键词：
分类号：R9(药学)
论文发表日期：2006-03-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 124-126 )
英文信息